General information about Jardiance Met (Empagliflozin 12.5 Mg/Metformin 1000 Mg) In USA (Synjardy Pills).
Buy Jardiance Met (Empagliflozin 12.5 Mg/Metformin 1000 Mg) is a prescription medicine belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes,
US FDA approves Jardiance Met to treat adults living with heart failure with reduced ejection fraction.
Jardiance Met 12.5mg/1000mg Tablet is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
It helps in proper utilisation of insulin, thereby lowering the blood sugar level.Belongs to a group of antidiabetic medicines (sodium-glucose co-transporter-2 (SGLT2) inhibitors).
Empagliflozin 12.5 Mg/Metformin 1000 Mg, sold under the brand name name Synjardy as well as Jardiance Met among others, is a fixed-dose combination anti-diabetic medication used to treat type 2 diabetes. It contains empagliflozin and metformin hydrochloride
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It is Mfg & developed by Boehringer Ingelheim Ltd In April 2016, the U.S. Food and Drug Administration (FDA) approved medicine used in the treatment of type 2 diabetes,
Empagliflozin was approved for medical use in the United States and in the European Union in 2014. It is on the World Health Organization’s List of Essential Medicines. In 2019, it was the 146th most commonly prescribed medication in the United States, with more than 10 million prescriptions
Inhibit Glucose Reabsorption and Expel the Excess in Your Urine:
The active ingredient in Jardiance Met (Empagliflozin 12.5 Mg/Metformin 1000 Mg), a sodium-glucose transporter 2 (SGLT2) inhibitor. When taken as directed, the SGLT2 inhibitor will inhibit the SGLT2 protein on your kidney that facilitates the reabsorption of glucose. This action will cause the glucose to be excreted in your urine, called glucosuria.
How to use Jardiance Met (Empagliflozin 12.5 Mg/Metformin 1000 Mg)
Jardiance Met is one of the newer drugs approved for treating those with type 2 diabetes, and is possibly safer than the other diabetic drugs that contain similar active ingredients.
Jardiance Met Pills is an antidiabetic medication utilized alone or in a blend with different drugs to treat type 2 diabetes in grown-up patients. This medication is likewise used to bring down the danger of cardiovascular passing in grown-up patients with type 2 diabetes mellitus
Taking Jardiance Met while eating sensibly, exercising, and not smoking can improve your blood sugar levels and your general well being. As you lose weight and consume less calories, you can also lower cholesterol levels and reduce blood pressure.
In Treatment of Type 2 diabetes mellitus:-
Jardiance Met Pills is two antidiabetic medicines: Empagliflozin and Metformin.
Empagliflozin is a type of medicine known as a sodium-glucose co-transporter-2 (SGLT2) inhibitor. It reduces blood sugar levels in people with diabetes. It does this by helping remove excess sugar from your body through your pee.
Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients. It lowers your blood sugar levels by improving how your body handles insulin. Altogether, they lower blood glucose more effectively
Only insulin can ‘unlock’ these cells, but as type 2 diabetics are not producing enough insulin or your body is not using it properly, your body needs a way to keep a balance of glucose in your cells and a way to get rid of the excess. Jardiance Met is not an insulin, it is a glucose transporter.
What is it prescribed for?
- Lower blood sugar along with diet and exercise in adults with type 2 diabetes
- Reduce the risk of cardiovascular death in adults with type 2 diabetes who also have known cardiovascular disease
- Reduce the risk of cardiovascular death and hospitalization for heart failure (when the heart is weak and cannot pump enough blood to the rest of your body) in adults with heart failure.
This medicine is not recommended for use in patients suffering from type 1 diabetes or diabetic ketoacidosis.
Jardiance Met 12.5/1000 Mg Pills is an antidiabetic medication. It works by removing excess sugar from your body through urine.
Jardiance Met 12.5/1000 Mg contains empagliflozin that works by blocking sodium glucose co-transporter protein in the kidneys which helps in eliminating blood glucose through urine thereby controlling blood sugar levels in type 2 diabetic patients.
Metformin works by making it easier for your cells to absorb and use glucose from your blood. It also decreases the amount of glucose made by your liver and absorbed in your intestines.
Jardiance is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works in your kidneys to prevent glucose from being reabsorbed so it ends up in your urine. What’s more, Jardiance has a similar effect on sodium (salt), which has benefits for heart failure, heart disease, and kidney disease.
When taken together, the way Jardiance and metformin work can have additional benefits for your heart and kidneys.
Empagliflozin works in the kidneys to prevent absorption of glucose (blood sugar). This helps lower the blood sugar level. Metformin reduces the absorption of sugar from the stomach, reduces the release of stored sugar from the liver, and helps your body use sugar better. It does not help patients who have insulin-dependent or type 1 diabetes. Type 1 diabetic patients must use insulin injections.
How and when to take & Dosage of Jardiance Met Pills :-
- Direction of use/Take :-
- Swallow the tablet whole with water,. Do not crush or chew the medicine.
- You can take the tablet with or without food
- You can take the tablet at any time of the day. However, try to take it at the same time each day.
This will help you to remember to take it.
Dosage of Jardiance Met 12.5/1000 Mg :-
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For type 2 diabetes, to lower risk of cardiovascular death in patients with type 2 diabetes and heart disease, and to lower risk of cardiovascular death and hospitalization in patients with heart failure:
For oral dosage form :-
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- Adults—At first, 1 or 2 tablets a day with food in the morning./once or twice a day with food/ Your doctor may increase your dose as needed and tolerated. However, the dose is usually not more than 25 mg of empagliflozin and 2000 mg of metformin per day.
- Children—Use and dose must be determined by your doctor.
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Take JARDIANCE MET twice daily with meals; with gradual dose escalation to reduce the gastrointestinalside effects due to metformin
- Your doctor will prescribe the strength that is right for you. Do not change your dose unless your doctor has told you to.
Why are Jardiance and metformin sometimes prescribed together?
The American Diabetes Association (ADA) typically recommends metformin as a first-choice medication, depending on your blood glucose goals and other factors.
But there are certain reasons why adding a medication like Jardiance may make sense — either initially or later on.
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You also have heart failure. Jardiance is approved to treat two of the most common types of heart failure. People with and without Type 2 diabetes can take it for this reason.
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You also have heart disease. Even if you don’t have heart failure, you can also benefit from Jardiance. If you have existing heart disease, it can lower the risk of death related to the condition.
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You also have kidney disease. Other SGLT2 inhibitors, like Invokana (canagliflozin) and Farxiga (dapagliflozin), are approved for chronic kidney disease (CKD). Jardiance isn’t approved for CKD yet, but it may be soon. Studies show that it can slow down kidney problems from getting worse and lower the risk of heart disease-related death in people with CKD.
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You aren’t able to meet your blood glucose goals with metformin alone. If you’re not quite at your goal, adding another medication may help. Jardiance isn’t the preferred choice in this situation, but it may be considered if other options aren’t appropriate.
Keep in mind: There are other medications with similar benefits for heart and kidney disease, including glucagon-like peptide-1 (GLP-1) agonists. Your healthcare provider will decide if adding Jardiance or different medication is right for you.
Before taking Empagliflozin & Metformin , inform your doctor if you:-
Talk to your doctor, pharmacist or nurse before taking this medicine, and during treatment:
- If you have “type 1 diabetes”. This type usually starts when you are young and your body does not produce any insulin. You should not take Jardiance to treat your type 1 diabetes
- If you have serious kidney problems – your doctor may limit your dose to 10 mg once a day or ask you to take a different medicine
- If you have serious liver problems – your doctor may ask you to take a different medicine.
- Diabetic ketoacidosis (a complication of diabetes with high blood sugar and rapid weight loss, nausea, or vomiting.
- If you have a serious infection of the kidney or the urinary tract with fever. Your doctor may ask
you to stop taking Jardiance until you have recovered
Do not take Jardiance Met if you:
- Have severe kidney problems, end stage renal disease, or are on dialysis
- have a condition called metabolic acidosis or diabetic ketoacidosis (increased ketones in the blood or urine)
- are allergic to empagliflozin (JARDIANCE), metformin,
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Side Effect while Taking Medicine:-
The most common side effects include hypoglycaemia (low blood sugar levels) when the medicine is taken with a sulphonylurea or insulin, infections of the urinary tract and genitals, and increased urination
Medicine Summery and Uses:-
| Drug | : | Jardiance Met/Synjardy(Empagliflozin 12.5 Mg/Metformin 1000 Mg |
| Pharmacological Category | : | Sodium Glucose Cotransporter-2 Inhibitor |
| Therapeutic Indication | : | Type 2 diabetes mellitus,Heart failure |
| Dosage Forms Brand |
: | Tablet |
Things To Remember to Patient (Diet & Lifestyle Advise):-
- Try to quit smoking and reduce intake of carbohydrate-rich food like potato, rice, mangoes, bread, sugar etc.
- Remember, lifestyle modifications are the most important step in controlling blood sugar levels.
Pharmacist tips for Proper Use of Jardiance Met :-
You must check your blood sugar regularly to be sure Jardiance is helping you. Limit your alcohol consumption as it can cause a rise or fall in your glucose levels.
- Keep Jardiance Met out of children’s reach and away from pets.
- Jardiance Met is only prescribed to type 2 diabetics.
Be aware that Jardiance Met may lower your blood pressure so remember to tell your doctor if you are currently taking hypertension drugs to avoid possible fainting, blurry vision, or nausea from a sudden drop in pressure.
Knowing the ideal storage care for (Jardiance Met ):-
- Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton after “EXP.” The expiry date refers to the last day of that month.
- Store in the original package in order to protect from moisture.
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Jardiance Met (empagliflozin and metformin hydrochloride) is indicated as an adjunct to diet and exercise to improve glycemic control in adult patients with type 2 As a result, it lowers blood sugar levels in diabetics. Shop Now from Our Online store.
Jardiance Met is a prescription medicine used to: lower blood sugar along with diet and exercise in adults with type 2 diabetes; reduce the risk of cardiovascular disease.
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FAQs:
Q.How many days should I take the Jardiance Met 12.5/1000Mg tablet?
The number of days that any medicine must be taken varies from patient to patient; and case to case. It is important to keep your blood glucose levels under control as any fluctuations in your blood glucose levels may cause serious problems. So always stick to your doctor’s suggestion about how many days to take this medicine.
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