General information about Kombiglyze XR Pills Have 5 mg saxagliptin (immediate release) and 500 mg
metformin (modified release) In USA.
Buy Kombiglyze XR (Saxagliptin 5 Mg & Metformin 500 Mg) medicine is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Kombiglyze XR is indicated as an adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes mellitus when treatment with both saxagliptin and metformin is appropriate.
Kombiglyze XR is used to lower blood sugar levels in patients with type 2 diabetes mellitus along with diet and exercise.
may also be used in combination with other medicines including insulin, a sulfonylurea (such as gliclazide) or a SGLT2 inhibitor (such as dapagliflozin) along with diet and exercise to treat type 2 diabetes.
‘Kombiglyze XR” is an oral hypoglycemic (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class
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It is Mfg & developed by Astrazeneca Ltd , the U.S. Food and Drug Administration (FDA) approved medicine used in the treatment of type 2 diabetes, approved by the U.S. Food and Drug Administration (FDA) on November 5, 2010, is now available by prescription in pharmacies across the United States.
AstraZeneca is a global, innovation-driven biopharmaceutical business with a primary focus on the discovery, development and commercialization of prescription medicines.
Take Kombiglyze XR to Help Control Your Type 2 Diabetes:-
Kombiglyze XR 5mg/500mg is belongs to a group of medicines known as antidiabetics, used in the treatment of type 2 diabetes in adults.
Kombiglyze XR 5mg/500mg is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control blood sugar levels.
People with type 2 diabetes either do not produce enough insulin, or the insulin produced is unable to perform its function in the body (insulin resistance).
Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.
How to use Kombiglyze XR (Saxagliptin 5 Mg & Metformin 500 Mg) :–
Kombiglyze XR contains Saxagliptin & Metformin which belongs to a group of medicines called oral anti-diabetics.
Kombiglyze XR is used for adult patients aged 18 years and older with ‘type 2 diabetes’, if the disease cannot be adequately controlled with one oral anti-diabetic medicine, diet and exercise.
In Treatment of Type 2 diabetes mellitus With Onglyza Pills:-
Type 2 diabetes mellitus is a condition in which your body does not make enough insulin and the insulin that your body produces does not work as well as it should. Your body can also make too much sugar.
When this happens, sugar (glucose) builds up in the blood and can lead to serious medical problems.The main goal of treating diabetes is to lower your blood sugar to a normal level.
What is it prescribed for?
Kombiglyze XR contains two active ingredients, saxagliptin and metformin hydrochloride (modified release). Saxagliptin is a member of a class of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors),
Metformin belongs to a class of medicines called biguanides. Saxagliptin and metformin work together to lower blood sugar levels in patients with type 2 diabetes mellitus.
- Treat type 2 diabetes mellitus in adults
- Type II Diabetes Mellitus is a condition in which your body cannot make or use the insulin it makes effectively, to move sugar from the blood into the cells for use as energy.
This medicine is only available with a doctor’s prescription.
Saxagliptin work by blocking the action of DPP-4/dipeptidyl peptidase-4 (an enzyme which destroys the hormone ‘Incretin’). The enzyme ‘Incretins’ help produce more insulin only when required and reduce blood sugar produced by the liver when not needed.
How and when to take & Dosage of Kombiglyze XR:-
How to take ”Kombiglyze XR“
- Follow all directions given to you by your doctor or pharmacist carefully.
- They may differ from the information contained in this leaflet.
- If you do not understand the instructions on the pack ask your doctor or pharmacist for help.
How to take it:
- Swallow your KOMBIGLYZE XR tablets whole with a full glass of water.
- KOMBIGLYZE XR tablets must not be chewed or crushed.
How much to take:
Dosage of Kombiglyze XR Pills For Patients :-
- The recommended dosage of KOMBIGLYZE XR should generally be administered once daily with the evening meal,
- The maximum daily recommended dosage is 5 mg for saxagliptin and 2000 mg for metformin extended-release.
Use in children and adolescents:-
Kombiglyze XR is not recommended for children and adolescents under 18 years. It is not known if this medicine is safe and effective when used in children and adolescents under 18 years of age.
Your Doctor will tell you how many KOMBIGLYZE XR tablets to take and how often you should take them. The dose varies from person to person. Your doctor will decide the right dose for you. .
If you forget to take Kombiglyze XR:-
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
If you stop taking Kombiglyze XR:-
Keep taking Kombiglyze XR until your doctor tells you to stop. This is to help keep your blood sugar under control.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist
Before Kombiglyze XR is Prescribed to You:-
Tell your doctor if you are breast feeding, pregnant, or trying to conceive before starting on Kombiglyze XR to be certain of its safety.
Discuss all current medical conditions or allergies you have and list any over the counter and Rx drugs you take or use to avoid possible negative interactions when taking Kombiglyze XR.
There is no cure for diabetes so you must continue taking Kombiglyze XR as prescribed and have a diet plan to regulate healthy sugar levels.
Do not take Kombiglyze XR:-
- if you are allergic to saxagliptin & Metformin or any of the other ingredients of this medicine.
Warnings and precautions:- Talk to your doctor or pharmacist before taking Kombiglyze XR Medicine.
- Heart failure
- liver problems
- kidney problems
- Your doctor will do some tests for kidney function at the start of treatment and regularly while you are on treatment.
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Side Effect to Kombiglyze XR :-
- Common side effects may include:-
- Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
- Upper respiratory tract infection
- Urinary tract infection
- Headache
Medicine Summery and Uses:-
| Drug | : | Kombiglyze XR (Saxagliptin & Metformin) |
| Pharmacological Category | : | Dipeptidyl Peptidase-4 Inhibitors |
| Therapeutic Indication | : | Type 2 diabetes mellitus,Heart failure |
| Dosage Forms Brand |
: | Tablet |
Things To Remember to Patient (Diet & Lifestyle Advise):-
- Avoid intake of alcoholic beverages with Pills as it can make you dehydrated and affect your sleep.
- Remember, lifestyle modifications are the most important step in controlling blood sugar levels.
Pharmacist tips for Proper Use of Kombiglyze XR:-
1) Your A1C test measures your blood sugar over time, usually 2-3 months.
Knowing the ideal storage care for :-
- Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton after “EXP.” The expiry date refers to the last day of that month.
- This medicine does not require any special storage conditions.
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Kombiglyze XR is a prescription medicine used to indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
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FAQs:
Q.What is Kombiglyze XR used to treat?
It is combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus.
Q.What class is Kombiglyze XR?
Q.Is Kombiglyze the same as metformin?
Kombiglyze XR is a combination of two prescription medications called saxagliptin and metformin hydrochloride that are available as generic drugs.
Q.Is Kombiglyze a DPP-4?
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